Dr. Loh: What now, vaccine makers?

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Dr. Irving Kent Loh

In this third summer of COVID, when pandemic fatigue has overwhelmed most of us, except for those who still think this virus is a manufactured figment of George Soros, Bill Gates, and Hillary Clinton, we still yearn for that elusive light at the end of this seemingly inevitable tunnel. With the early iterations of SARS-CoV-2, the amazingly rapid development of incredibly effective mRNA vaccines seemed to tip the battle in humanity’s favor and victory seemed near.

But then biology happened. Or more precisely, the laws of evolution prevailed. As I have written about many times previously, with each reproductive generation, the virus tinkered with its genetic code to find a workaround to the spike protein targets on which the mRNA vaccines had focused in order to interfere with the virus’ ability to infect our vulnerable cells and provide the opportunity to reproduce, which is the prime directive of life. Changes in the viral genome altered the spike protein sufficiently so that the mRNA vaccines began losing their efficacy, combined with the waning of the windows of vaccine or infection-induced protection, allowed variants of concern to emerge to infect humans who lacked the immunologic protection to defending themselves against infection (but protection against serious disease and mortality seems to endure).

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